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• 4.13 Patch Notes

BackgroundPhysical therapy treatment of patients with lymphedema includes treatment based on the principles of ‘Complete Decongestive Therapy’ (CDT). CDT consists of the following components; skin care, manual lymphatic drainage, bandaging and exercises. The scientific evidence regarding what type of treatment is most effective is sparse. The objective of this study is to investigate whether CDT is equally effective if it includes manual lymphatic drainage or not in the treatment of arm lymphedema among patients with breast cancer. Methods/DesignA randomized, single-blind, equivalence trial. A total of 160 breast cancer patients with arm lymphedema will be recruited from 3 hospitals and randomized into one of two treatment groups A: Complete Decongestive Therapy including manual drainage or B: Complete Decongestive Therapy without manual lymphatic drainage. The intervention period will be approximately 4 weeks followed by a 6 month follow-up period (7 months from baseline).

Primary outcome variable: the percentage volume reduction of lymphedema (%) from baseline to 7 months. Secondary outcome variables: Differences from baseline to week 4 and from week 4 to month 7 in circumference of the arm (cm), body weight (kg), patient sensation of heaviness (scale range: 0–10), patient sensation of tension (scale range: 0–10), and quality of life (EQ-5D-5 L-questionnaire).All measurements are standardized and will be performed before randomization, after 4 weeks and after 7 months.

4.13 Patch Notes

DiscussionThis randomized controlled study seeks to provide data on an effective treatment for patients with breast cancer related arm lymphedema and which at the same time causes minimal patient inconvenience. Trial registrationClinicalTrials.gov: Identifier.

The intervention period is approximately 4 weeks followed by 6 months follow-up period. Overall length of the study is 7 months. Bthenum driver windows 7 download iso. Primary endpoint will be 7 months from baseline.The patients complete baseline measurements before the randomization. ParticipantsPatients with breast cancer related lymphedema will be recruited from the Hospital of Southwest Jutland, Lillebaelt Hospital, and the Hospital of Southern Jutland. In clinical practice it is important to investigate the methods used and elucidate those which are most effective. Several studies have been published focusing on the effect of Complete Decongestive Therapy (CDT), an often used method in the treatment among breast cancer patients with arm lymphedema.

Manual lymphatic drainage is a time-consuming component in CDT. However, there is not sufficient scientific evidence supporting the use of manual lymphatic drainage in preventing or treating arm lymphedema. Moreover, there is focus on the issue of resources; how we can identify the most effective arm lymphedema treatment and achieve the desired clinical benefit with minimal patient inconvenien.